TY - JOUR T1 - Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing JO - Revista de Gastroenterología de México T2 - AU - Rodríguez-Wong,U. AU - Rodríguez-Medina,U. AU - Medina-Murillo,G.R. SN - 2255534X M3 - 10.1016/j.rgmxen.2019.01.003 DO - 10.1016/j.rgmxen.2019.01.003 UR - http://revistagastroenterologiamexico.org/en-randomized-clinical-trial-with-topical-articulo-S2255534X19300052 AB - Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy. There were 26 patients in each group. Group A received topical diltiazem in the anal region three times a day. Group B received a placebo. Cicatrization time was documented for 6 weeks through digital photography. Mean healing time for the group treated with diltiazem was 3.19 weeks (22.33±0.884 days) and 3.92 weeks (27.44±1.130 days) for the control group (p=0.012 95% CI). At week three, the wounds in 73.07% of the patients in the diltiazem group had healed, compared with 46.15% of the patients in the control group. ER -